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Efficacy of Tranexamic acid in Melasma

Microneedling with Topical Tranexamic acid and Topical Hydroquinone versus Microneedling and Topical Hydroquinone for treatment of Melasma : Randomized Clinical Trial

Status
Active, not recruiting
Phases
Unknown
Study type
Interventional
Source
CTRI
Registry ID
CTRI/2022/12/047814
Enrollment
40
Registered
2022-12-01
Start date
Unknown
Completion date
Unknown
Last updated
2023-01-09

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Health Condition 1: L811- Chloasma

Interventions

Intervention1: Tranexamic Acid: Topical 10% Tranexamic acid (2ml) is applied over one side after microneedling at 0 week, 4 week and 12 week Control Intervention1: Normal Saline: Normal saline is appl

Sponsors

AIIMS JODHPUR
Lead Sponsor

Eligibility

Inclusion criteria

Inclusion criteria: All melasma patients with bilateral symmetrical melasma are included

Exclusion criteria

Exclusion criteria: Irregular menstruation Pregnancy

Design outcomes

Secondary

MeasureTime frame
Side effects, change in mMASI,Physician Global AssesmentTimepoint: 4 weeks, 8 weeks, 12 weeks—

Primary

MeasureTime frame
Efficacy of topical Tranexamic acid will be assessed compared to normal saline using modified MASI scoreTimepoint: At 4 weeks, 8 weeks, 12 weeks—

Countries

India

Contacts

Public ContactNagbhushan Hegde

AIIMS JODHPUR

doc.trinity@yahoo.com7297895727

Outcome results

None listed

Source: CTRI (via WHO ICTRP) · Data processed: Feb 4, 2026