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To Compare the effect of intravenous ketamine and dexmeditomidine on postoperative analgesia in ent surgeries

comparison of effect of intravenous ketamine and dexmeditomidine infusion on postoperative analgesia in otorhinolaryngeal surgeries: a double blinded randomised control trial

Status
Active, not recruiting
Phases
Unknown
Study type
Interventional
Source
CTRI
Registry ID
CTRI/2022/11/047801
Enrollment
120
Registered
2022-11-30
Start date
Unknown
Completion date
Unknown
Last updated
2023-01-09

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Health Condition 1: H939- Unspecified disorder of ear

Interventions

Intervention1: Intraoperative intravenous infusion of ketamine: Intraoperative iv infusion of ketamine at 0.25 mg/kg/hr started post intubation till surgical closure Intervention2: Intraoperative intr

Sponsors

AIIMS JODHPUR
Lead Sponsor

Eligibility

Inclusion criteria

Inclusion criteria: Patients undergoing (Elective) otorhinolaryngeal surgeries under general anaesthesia among ASA I and II patients

Exclusion criteria

Exclusion criteria: 1.Refusal of informed consent 2.Hemodynamic instability 3.History of chronic pain/analgesic use 4.Patient with underlying opioid abuse 5.Contraindications to any of the study drugs 6.Endoscopic surgeries 7.Use of beta-blockers or calcium-channel blockers 8.pregnancy or lactation

Design outcomes

Primary

MeasureTime frame
To find time to first rescue analgesic after intraoperative infusion of intravenous ketamine and dexmedetomidineTimepoint: First 24 postoperative hours—

Secondary

MeasureTime frame
1.Numeral Rating Score (NRS) for pain in 24 hours postoperatively. 2.Amount of rescue analgesics in 24hours postoperatively 3.Postoperative sedation (Ramsay Sedation Score) 4.Post operative complications as nausea and vomiting, constipation, urinary retention,etc 5.Patient satisfaction score Timepoint: First 24 postoperative hours—

Countries

India

Contacts

Public ContactAnjaly Nair V

AIIMS JODHPUR

docbpali@gmail.com9588089378

Outcome results

None listed

Source: CTRI (via WHO ICTRP) · Data processed: Feb 4, 2026