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Effect of DEC drug in the treatment of allergic rhinitis patients.

A comparative study on the efficacy of diethylcarbamazine as an adjuvant therapy with standard therapy in the treatment of allergic rhinitis

Status
Active, not recruiting
Phases
Unknown
Study type
Interventional
Source
CTRI
Registry ID
CTRI/2022/11/047741
Enrollment
235
Registered
2022-11-28
Start date
Unknown
Completion date
Unknown
Last updated
2023-01-09

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Health Condition 1: D80-D89- Certain disorders involving the immune mechanism

Interventions

Intervention1: DEC drug: After the initial assessment, the patients will be diagnosed and categorized into one of the four groups as Mild intermittent Allergic Rhinitis, Mild persistent Allergic Rhini

Sponsors

Prem Davis
Lead Sponsor

Eligibility

Inclusion criteria

Inclusion criteria: 1. Age: >18 years 2. Symptoms of Allergic Rhinitis â?? two or more symptoms of anterior or posterior rhinorrhea, Sneezing, nasal blockage, itching, watering of eyes, nasal and pharyngeal itching during two or more consecutive days for more than one hour on most days. 3. Patients not on any antiallergic medications and DEC for the past 2 weeks.

Exclusion criteria

Exclusion criteria: Exclusion Criteria 1. Pregnant Women 2. K/C/O Diabetes Mellitus with Random Blood Sugar values of >200mg/dl with oral and injectable antidiabetic drugs. 3. Allergic Fungal Rhinosinusitis 4. Past History of Nasal Surgery 5. Immunocompromised Patients (Patient with History of frequent infection, immunosuppressant therapy, history of chemo or radiotherapy) 6. Tumors of nose and paranasal Sinuses. 7. Hypersensitivity to Diethylcarbamazine

Design outcomes

Primary

MeasureTime frame
Pre-treatment Assessment and Post-treatment Assessment was compared with Total Nasal Symptom Score, Absolute eosinophils count, nasal smear for eosinophil, Diagnostic Nasal Endoscopy and Mini Rhinoconjuctivitis Quality of Life QuestionnaireTimepoint: Assessment will be made at baseline and after 21 days of treatment.

Secondary

MeasureTime frame
NilTimepoint: Nil

Countries

India

Contacts

Public ContactPrem Davis

Sri Venkateshwaraa Medical College Hospital and Research Centre, Ariyur, Puducherry

drvprabu@gmail.com9787138601

Outcome results

None listed

Source: CTRI (via WHO ICTRP) · Data processed: Feb 4, 2026