Medicine for headache in child

Comparison of efficacy of oral naproxen and ibuprofen for management of acute headache in children with migraine aged 5-18 years: a single blind, randomized controlled trial - NIM-C

Status

Active, not recruiting

Phases

Phase 2Phase 3

Study type

Interventional

Source

CTRI

Registry ID

CTRI/2022/11/047712

Enrollment

132

Registered

2022-11-28

Start date

Unknown

Completion date

Unknown

Last updated

2023-01-09

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Health Condition 1: G439- Migraine, unspecified

Interventions

Intervention1: Naproxen oral tablet: Naproxen oral 7 mg/kg/day single dose (only once) when headache occurs Control Intervention1: Ibuprofen oral: Ibuprofen 10 mg/kg/dose single dose orally (only once

Eligibility

Inclusion criteria

Inclusion criteria: Children diagnosed to have migraine with/without aura

Exclusion criteria

Exclusion criteria: 1.Patient diagnosed with another co-existent headache disorder 2.Chronic renal, gastrointestinal diseases, acid-peptic disease, hepatic, pulmonary or cardiac diseases

Design outcomes

Primary

Measure	Time frame
The proportion of children who experience pain-freedom two hours after the intake of the study drug in each arm Timepoint: Two hours after taking the medication	—

Secondary

Measure	Time frame
Proportion of patients with sustained pain-freedom at 24 hoursTimepoint: At 24 hours	—

Countries

India

Contacts

Public ContactPRATEEK KUMAR PANDA

AIIMS, RISHIKESH

drprateekpanda@gmail.com9650149735

Outcome results

None listed

Source: CTRI (via WHO ICTRP) · Data processed: Feb 4, 2026