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Effect of hyperosmotic stress on red blood cell behavior

Effect of hyperosmotic stress on red cell morphometrics and hemolysis

Status
Active, not recruiting
Phases
Unknown
Study type
Observational
Source
CTRI
Registry ID
CTRI/2022/11/047704
Enrollment
17
Registered
2022-11-28
Start date
Unknown
Completion date
Unknown
Last updated
2023-01-09

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

None listed

Interventions

Control Intervention1: nil: nil

Sponsors

PG Research Grant
Lead Sponsor

Eligibility

Inclusion criteria

Inclusion criteria: Healthy volunteers above the age of 18 years, males with hemoglobin (Hb) levels in the range 14 to 17 g% and females with Hb levels in the range 11 to 15 g% and who are not under medication are included in this study. Only persons knowing to read and write English will be included.

Exclusion criteria

Exclusion criteria: ï?¼ Vulnerable subjects such as pregnant females and subjects under chronic infections and diabetes are excluded.

Design outcomes

Primary

MeasureTime frame
This study proposes to explore the structural variations of RBCs by a computerized image analysis approach as well the extent of hemolysis spectrophotometrically when RBCs are subjected to hyperosmotic stress, in vitro.Timepoint: From date of CTRI approval till September 30 2023—

Secondary

MeasureTime frame
nilTimepoint: nil—

Countries

India

Contacts

Public ContactAntony O F

Kasturba Medical College-Manipal, MAHE

sanu.susan@manipal.edu9448078874

Outcome results

None listed

Source: CTRI (via WHO ICTRP) · Data processed: Feb 4, 2026