A clinical trial comparing different materials in treatment invloving incompletely formed teeth

Comparative evaluation of Hydrogel Scaffold Loaded with Chitosan, double antibiotics and PRF in Regenerative Endodontic treatment of Permanent Immature Non- vital Teeth

Status

Active, not recruiting

Phases

Phase 2

Study type

Interventional

Source

CTRI

Registry ID

CTRI/2022/11/047698

Enrollment

Registered

2022-11-28

Start date

Unknown

Completion date

Unknown

Last updated

2023-01-09

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Health Condition 1: K041- Necrosis of pulp

Interventions

Intervention1: Regenerative Endodontic Treatment using DAP loaded hydrogel scaffold: Under local anaestheia, access cavity is prepared, under rubber dam canal is negotiated and irrigation is done thor

Eligibility

Inclusion criteria

Inclusion criteria: Clinical cases with immature asymptomatic non- vital permanent teeth will comprise the study. Medically fit persons with necrotic pulp in permanent teeth with open apex that show no reponse on thermal test and electric pulp testing.

Exclusion criteria

Exclusion criteria: Patients with medical conditions like cardiac problems, pregnant patients, diabetic patients, bleeding tendencies, HIV+ patients, hepatitis B. All patients will go through HIV screening

Design outcomes

Primary

Measure	Time frame
root lengthening, dentinal wall thickening and apical closureTimepoint: 6months, 12 months	—

Secondary

Measure	Time frame
no evidence of progression of periapical pathological findings in the radiographTimepoint: 6months, 12months	—

Countries

India

Contacts

Public ContactHarshitaa Aggarwal

Faculty of Dental Sciences, IMS, BHU, Varanasi

aggarwalharshitaa@yahoo.in7289001881

Outcome results

None listed

Source: CTRI (via WHO ICTRP) · Data processed: Feb 4, 2026