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Clinical trial on scarring alopecia (where hair roots are permanently lost because of scarring)

A cross sectional study on clinical, trichoscopic, histopathological correlation and hair follicle stem cell marker CD34 expression in patients of cicatricial alopecia. - None

Status
Active, not recruiting
Phases
Unknown
Study type
Observational
Source
CTRI
Registry ID
CTRI/2022/11/047658
Enrollment
30
Registered
2022-11-25
Start date
Unknown
Completion date
Unknown
Last updated
2023-01-09

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Health Condition 1: L669- Cicatricial alopecia, unspecified

Interventions

None listed

Sponsors

Indian association of dermatologist venereologist and leprologist
Lead Sponsor

Eligibility

Inclusion criteria

Inclusion criteria: All cases of acquired cicatricial alopecia affecting any body part will be included who are willing to sign informed consent form, in case of minor, parent will have to sign informed consent form.

Exclusion criteria

Exclusion criteria: 1. Patients who are not willing to sign informed consent form 2. Patients with non scarring alopecia 3. Patients with traumatic cicatricial alopecia (Mechanical injury, Thermal injury, Electrical burns, Traction alopecia (persistent), Trichotillomania (persistent), Factitious injury, etc ) 4. Patients with congenital cicatricial alopecia (Aplasia cutis, Focal dermal hypoplasia, Dystrophic epidermolysis bullosa, Incontinentia pigmenti, Conradi syndrome, Keratosis pilaris atrophicans faciei, Keratosis follicularis spinulosa decalvans, Darierâ??s disease, Porokeratosis of Mibelli, Epidermal nevus, Lamellar ichthyosis, Marieâ??Unna syndrome, Follicular hamartoma syndrome, Polyostotic fibrous dysplasia, Hallermannâ??Streiff syndrome, Incontinentia pigmenti, Rappâ??Hodgkin syndrome) 5. Patients with secondary cicatricial alopecia due to infections. 6. Patients with soft tissue and appendageal tumours which might affect expression of CD34. 7. Patients with haematological disorders and malignancy. 8. Cutaneous malignancy involving head and neck. 9. Patients with vascular tumours 10.Malignancy induced primary or secondary cicatricial alopecia except Alopecia Mucinosa 11.Patients with history of previous scalp procedure 12.Patients with hypertrophic scars or keloid in head and neck area except acne keloidalis nuchae 13.Pregnant and lactating females

Design outcomes

Primary

MeasureTime frame
To estimate the correlation between clinical, trichoscopic and histopathological findings and immunohistochemistry expression of hair follicle stem cell marker CD34 with duration of disease in patients of cicatricial alopecia.Timepoint: It is a cross sectional single visit study on day 0.

Secondary

MeasureTime frame
To estimate hospital-based prevalence of cicatricial alopecia. â?? To estimate correlation between clinical, trichoscopic and histopathological parameters in end stage cicatricial alopecia where there are no symptoms and histopathology reveals no inflammation.Timepoint: It is a cross sectional single visit study on day 0.

Countries

India

Contacts

Public ContactDr Megha Lakum

GCS medical college hospital and research center

dr.jignapadhiyar@gmail.com8799417752

Outcome results

None listed

Source: CTRI (via WHO ICTRP) · Data processed: Feb 4, 2026