Health Condition 1: H712- Cholesteatoma of mastoid
Conditions
Interventions
Intervention1: Introperative use of Dexmedetomidine and Magnesium: Patients in Group D will be given Dexmedetomidine bolus iv of 1 mcg/kg in 100 ml NS over 15 minutes before incision is made .This wil
Sponsors
St Johns Medical College and Hospital
Eligibility
Inclusion criteria
Inclusion criteria: 1)Adults aged 18-59 years posted for middle ear surgeries. 2)ASA 1 and 2 patients with well controlled co-morbidities
Exclusion criteria
Exclusion criteria: 1)Patients already on chronic analgesic medications 2)Obese patients BMI >30 3)Pregnant patients 4)Patients with h/o motion sickness,reflux and previous h/o post operative nausea , vomitting
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| To compare the efficacy of intraoperative use of Propofol, Dexmedetomidine and Magnesium sulphate for controlled hypotension (MAP of 55-65 mmHg) in middle ear surgeriesTimepoint: At 5,10,15,20,30,45,60,78,90,105 and 120 minutes | — |
Secondary
| Measure | Time frame |
|---|---|
| To assess oligemic field during the surgery. To compare the anaesthetic agent consumption (Oxygen, Air and Isoflurane ) at the end of the surgery. To compare the degree of postoperative pain and postoperative nausea and vomiting after Propofol , Dexmedetomidine and Magnesium sulphate in recovery period at 5 minutes, 30 minutes, 1 hour, 2hours and 8 hours. Timepoint: A)Oligemic field and anaesthetic agent at the end of surgery B) Post operative nausea and vomiting and post operative pain at early(5min,30 min) and late (1 hour , 2 hours and 8 hours) | — |
Countries
India
Contacts
Public ContactDrMManjuladevi
St.Johns Medical College
Outcome results
None listed