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Comparing the Combination of Dexmedetomidine and Lidocaine Infusion With Intravenous Lidocaine Infusion in Attenuating heart rate and blood pressure response to Laryngoscopy and Endotracheal Intubation in patients undergoing general anaesthesia.

Comparison of Combination of Low Dose Intravenous Dexmedetomidine and Lidocaine Infusion With Intravenous Lidocaine Infusion to Attenuate Haemodynamic Response to Laryngoscopy and Endotracheal Intubation in Adult Patients Undergoing General Anaesthesia.

Status
Active, not recruiting
Phases
Unknown
Study type
Interventional
Source
CTRI
Registry ID
CTRI/2022/11/047632
Enrollment
70
Registered
2022-11-24
Start date
Unknown
Completion date
Unknown
Last updated
2023-01-09

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Health Condition 1: - Health Condition 2: O- Medical and Surgical

Interventions

Intervention1: Administration of low-dose Dexmeditomidine and lidocaine combination and standard dose lidocaine and saline combination: Comparing the attenuation of haemodynamic response to laryngosco

Sponsors

Department of Anaesthesia
Lead Sponsor

Eligibility

Inclusion criteria

Inclusion criteria: Patients posted for elective surgeries under general anaesthesia. Patients of ASA grade I and II Adult patients(18-60) years

Exclusion criteria

Exclusion criteria: Hypertensive patients Previous history of coronary artery disease History of arrhythmias, pacemakers Patients allergic to Dexmedetomidine and/or Lidocaine Usage of beta blockers Emergency surgeries Full stomach Patients Pregnant and Paediatric Patients

Design outcomes

Primary

MeasureTime frame
measurement of Heart rate and Mean Blood PressureTimepoint: Measurement of heart rate and mean blood pressure at following intervals: 1.Arrival to Operation Theatre. 2.Two minutes after completion of infusion of the test drug. 3.Five minutes after completion of infusion of the test drug 4.Before induction of anaesthesia. 5.After induction of anaesthesia. 6.1, 3, 5, 10 minutes after laryngoscopy and endotracheal intubation—

Secondary

MeasureTime frame
To observe for any adverse effects such as bradycardia, hypotension, arrhythmiasTimepoint: intraoperatively—

Countries

India

Contacts

Public ContactUMA HARIHARAN

ABVIMS and Dr.RML Hospital

uma1708@gmail.com9811271093

Outcome results

None listed

Source: CTRI (via WHO ICTRP) · Data processed: Feb 4, 2026