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Effect of closing and not closing innermost layer of abdomen during open appendectomy on pain after surgery

Effect of Peritoneal Non-closure and Closure during Open Appendectomy on post-operative pain: A Randomized, Double-Blinded Study.

Status
Active, not recruiting
Phases
Unknown
Study type
Interventional
Source
CTRI
Registry ID
CTRI/2022/11/047615
Enrollment
140
Registered
2022-11-24
Start date
Unknown
Completion date
Unknown
Last updated
2023-01-09

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Health Condition 1: O- Medical and Surgical Health Condition 2: O- Medical and Surgical Health Condition 3: K358- Other and unspecified acute appendicitis

Interventions

Intervention1: Open Appendectomy- Non closure of peritoneum: In open appendectomy for acute appendicitis, not closing the peritoneal layer during surgery Control Intervention1: Open Appendectomy- Clos

Sponsors

JIPMER
Lead Sponsor

Eligibility

Inclusion criteria

Inclusion criteria: All patients aged 18 to 65 years, undergoing open appendectomy for acute appendicitis from July 2022 to June 2024.

Exclusion criteria

Exclusion criteria: 1. Perforated appendix on operation. 2. Presence of intra-abdominal abscess. 3. Localized or diffuse purulent fluid in the ab-dominal cavity. 4. Patients requiring Rutherford-Morrison incision 5. Pregnancy 6. Patients with chronic renal failure. 7. Patients with Diabetes mellitus. 8. Patients with known psychiatric or mental disorders. 9. Patients denying consent.

Design outcomes

Primary

MeasureTime frame
1. To compare the pain score using Visual Analogue Scale (VAS) on 1st postoperative day (24 hoours) following open appendectomy between patients having non-closure and closure of peritoneum while undergoing open appendectomy.Timepoint: 24 hours post surgery—

Secondary

MeasureTime frame
1. To compare the pain score using Visual Analogue Scale (VAS) on 2nd postoperative day (48 hours). 2. To compare the requirement of analgesics in the postoperative period. 3. To compare the incidence of surgical site infections between the two groups. 4. To compare the incidence of wound dehiscence in 30 days between the two groups. Timepoint: 48 hours post surgery 30 days post surgery—

Countries

India

Contacts

Public ContactDripta Ramya Sahoo

Jawaharlal Institute of Postgraduate Medical Education and Research

debasismbbs@gmail.com8763124660

Outcome results

None listed

Source: CTRI (via WHO ICTRP) · Data processed: Feb 4, 2026