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Pain relief with intravenous ketamine after cesarean section

THE EFFECT OF LOW DOSE INTRAVENOUS KETAMINE ON POSTOPERATIVE PAIN FOLLOWING CESAREAN SECTION WITH SPINAL ANESTHESIA

Status
Active, not recruiting
Phases
Phase 2Phase 3
Study type
Interventional
Source
CTRI
Registry ID
CTRI/2022/11/047573
Enrollment
96
Registered
2022-11-23
Start date
Unknown
Completion date
Unknown
Last updated
2023-01-09

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Health Condition 1: O80- Encounter for full-term uncomplicated delivery

Interventions

Intervention1: Low dose intravenous ketamine: Five minutes after delivery, women in the experimental group will be given 0.25 mg/kg intravenous ketamine via bolus dose Control Intervention1: Normal sa

Sponsors

Dr Chethana M
Lead Sponsor

Eligibility

Inclusion criteria

Inclusion criteria: ASA I to II Patients Female patients. Aged between 20 to 40years. Normal liver and renal function test, Coagulation profile. Undergoing Lower Segment Caesarean Section Surgery.

Exclusion criteria

Exclusion criteria: Patients with history of allergy to local Anaesthetics. Patients with history of mental disorders. Patient Refusal. Morbid obesity, Coagulopathy and significant cardiovascular respiratory, renal, hepatic or metabolic diseases or CNS disorders. Patients with hypertensive disorder due to any cause ( PIH)

Design outcomes

Primary

MeasureTime frame
Degree of post operative pain relief with single dose of intravenous ketamine during cesarean sectionTimepoint: A visual analogue score will be used to record the participants pain score at 1, 2, 6, 12 hours following surgery. Participants will be asked to rate the intensity of their pain in the scale of one (no pain at all) to 10 (very intense and unimaginable pain).

Secondary

MeasureTime frame
First rescue analgesia used. Total analgesic consumed in first 24hrs Hemodynamic parameters for 24 hours post operatively. Adverse effects, if any. Timepoint: Participants will be monitored for common side effects, such as nausea, vomiting, headache, hallucination, and itching, and the prevalence of such side effects will be recorded at 1,2,6 and 12 hrs following surgery.

Countries

India

Contacts

Public ContactDr S Rangalakshmi

Rajarajeswari medical college and hospital

rangbharat@gmail.com9901703030

Outcome results

None listed

Source: CTRI (via WHO ICTRP) · Data processed: Feb 4, 2026