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Comparison of two medicines in terms of efficacy in controlling shivering after surgery done under spinal anaesthesia.

Intrathecal dexmedetomidine vs intravenous dexmedetomidine as prophylaxis of post-spinal anesthesia shivering in urologic endoscopic surgery-A Randomized Prospective Trial

Status
Active, not recruiting
Phases
Unknown
Study type
Interventional
Source
CTRI
Registry ID
CTRI/2022/11/047557
Enrollment
60
Registered
2022-11-23
Start date
Unknown
Completion date
Unknown
Last updated
2023-01-09

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Health Condition 1: O- Medical and Surgical

Interventions

Intervention1: Intrathecal dexmedetomidine: 10mcg intrathecal dexmedetomidine+3ml 0.5% hyperbaric bupivacaine and 10ml saline immediately after block over 10mins Control Intervention1: Intravenous dex

Sponsors

Rohilkhand medical college and hospital
Lead Sponsor

Eligibility

Inclusion criteria

Inclusion criteria: American society of Anaesthesiologist (ASA) grade I or II. Either sex. Patient posted for elective urologic endoscopic surgeries.

Exclusion criteria

Exclusion criteria: Patients with contraindications of any type to Spinal anaesthesia Obesity (BMI >30kg/m2) Patient on clonidine as antihypertensive Patients receiving opioids for chronic analgesic therapy Allergy or intolerance to local anaesthetics Patients on beta blocker or known cardiac dysrhythmia

Design outcomes

Primary

MeasureTime frame
To Compare effects of both groups according to:- 1.Incidence of shivering following spinal anaesthesia 2.Severity of shivering following spinal anaesthesia by Crossley Mahajan scale 3.Level of sedation by Ramsay sedation scale 4.Temperature monitoring 5.Onset and duration of sensory block 6.Onset and duration of motor block 7.Incidence of complications-hypotension, bradycardia, nausea, vomiting Timepoint: 1.Shivering intensity monitored every 5mins for first 15mins and then every 15mins for next 4hrs after the block. 2.Sedation level observed and recorded every 30min for 4hrs after the block. 3.Heart rate,systolic BP, diastolic BP,Mean arterial pressure and temperature monitored every 5mins for 4hrs after the block.

Secondary

MeasureTime frame
1.Onset and duration of sensory block 2.Onset and duration of motor block 3.Incidence of complications-hypotension, bradycardia, nausea, vomiting Timepoint: The patient will be evaluated for sensory and motor block every 2minutes for first 20mins,every 3minutes for next 30minutes,every 10minutes for 60mins.

Countries

India

Contacts

Public ContactDr Nithin J

Rohilkhand medical college and hospital

docneehars@gmail.com8077104070

Outcome results

None listed

Source: CTRI (via WHO ICTRP) · Data processed: Feb 4, 2026