Health Condition 1: O- Medical and Surgical
Conditions
Interventions
Intervention1: Injection Ketamine 0.25mg/kg intravenous: Injection given intravenously at the time of anesthesia induction
Intervention2: Injection Ketamine 0.5mg/kg intravenous: Injection given intra
Sponsors
Mahatma Gandhi medical College and Hospital
Eligibility
Inclusion criteria
Inclusion criteria: American Society of Anaesthesiology class I and II Weight 50-70kgs Patients scheduled for elective supratentorial brain tumour surgeries more than 2.5cm ,symptomatic and with radiological evidence of raised Intracranial pressure
Exclusion criteria
Exclusion criteria: American Society of Anaesthesiology class III,IV and V Predicted difficult airway Non consenting patients History of allergy with Ketamine Pregnant and lactating females Patients with organ dysfunction
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| To compare Intracranial pressure by measuring Optic nerve sheath diameter with two different doses of Ketamine as compared to control groupTimepoint: 1) Before anesthesia induction 2) After 2 minutes of bag and mask ventilation 3) 5 minutes after endotracheal intubation | — |
Secondary
| Measure | Time frame |
|---|---|
| To compare haemodynamics between groupsTimepoint: 1) Before anesthesia induction 2) After 2 minutes of bag and mask ventilation 3) 5 minutes after endotracheal intubation | — |
Countries
India
Contacts
Public ContactRavindra Singh Sisodia
Mahatma Gandhi Medical College and Hospital
Outcome results
None listed