Health Condition 1: O- Medical and Surgical
Conditions
Interventions
Intervention1: Dexmedetomidine: Group D 0.5 - Patients will receive 0.5 mcg/kg of dexmedetomidine in 20 ml normal saline
Group D 0.7 - Patients will receive 0.7 mcg/kg of dexmedetomidine in 20 ml norm
Sponsors
Department of Anaesthesia
Eligibility
Inclusion criteria
Inclusion criteria: Patients belonging to American Society of Anaesthesiologist Grade I and II, posted for elective surgery under general anaesthesia
Exclusion criteria
Exclusion criteria: Patient refusal Patient with known allergy to study drug Patients with history of recent myocardial infarction ( patients with epilepsy, hepatic failure, psychiatric disease, sepsis or systemic infections, neurological disease patients with major illnesses like bronchial asthma, chronic cough, upper respiratory tract infection 2 weeks prior to surgery patients who had received analgesics or sedatives within previous 24 hours
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| To study and compare the incidence and severity of etomidate induced myoclonus in all 3 groupsTimepoint: after induction with etomidate for 3 minutes | — |
Secondary
| Measure | Time frame |
|---|---|
| 1.To study and compare the incidence of adverse effects of dexmedetomidine 2.To study and compare the effect of different doses of dexmedetomidine on attenuation of stress response to laryngoscopy and intubationTimepoint: 1. from onset of action of dexmedetomidine to injection of etomidate 2. before starting dexmedetomidine infusion till 5 minutes after intubation | — |
Countries
India
Contacts
Public ContactDr Seema Jindal
Baba Farid university of Health Sciences
Outcome results
None listed