Health Condition 1: G473- Sleep apnea
Conditions
Interventions
Intervention1: AUTO CPAP therapy: AUTO CPAP therapy
for 4 weeks
Intervention2: FIXED CPAP/BIPAP therapy: Fixed CPAP/BIPAP therapy
for 4 weeks
Control Intervention1: NIL: NIL
Sponsors
Prakhar Agarwal
Dr Abhishek Goyal
Dr Alkesh Khurana
Eligibility
Inclusion criteria
Inclusion criteria: Recently diagnosed patients with moderate to severe OSA who achieve successful titration with CPAP or BIPAP
Exclusion criteria
Exclusion criteria: Pregnant females; Patients with Cardiac failure; Patients with Central Sleep Apnea Patients with Psychiatric, and neurologic disorders; Patients who change their antihypertensive medications during course of study; Patients with craniofacial abnormalities which can hamper use of CPAP; Patients currently using PAP therapy;
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Change in 24 hr mean Systolic and diastolic Ambulatory Blood Pressure Monitoring (ABPM) parameters in Fixed pressure Continous positive airway pressure (FP-CPAP) therapy and Auto adjusting continous positive airway pressure (APAP) therapy groups.Timepoint: At baseline, at 4 weeks of initial PAP therapy,after 1 week of washout period and at 4 weeks of other PAP therapy | — |
Secondary
| Measure | Time frame |
|---|---|
| Change in Office Blood Pressure, 24 hr heart rate and night time dipping patternTimepoint: At baseline, at 4 weeks of initial PAP therapy, after 1 week of washout period and after 4 weeks of other PAP therapy | — |
Countries
India
Contacts
Public ContactDr Abhishek Goyal
ALL INDIA INSTITITUE OF MEDICAL SCIENCES BHOPAL
Outcome results
None listed