Health Condition 1: R625- Other and unspecified lack of expected normal physiological development in childhood
Conditions
Interventions
Intervention1: NIL: NIL
Intervention2: Lysine drink
: Lysine drink with orange flavour
Supervised feeding for a maximum of 6 days in a week for the total duration of 3 months.
Control Intervention1:
Sponsors
Indo-French Centre for the Promotion of Advanced Research (IFCPAR/CEFIPRA)
Eligibility
Inclusion criteria
Inclusion criteria: normal and malnourished children n equal to 25 each Consent, assent, understanding of the study by the parent or guardians. Children with good general health and without clinical signs of physical disability will be recruited from local schools with a normal height for age Z score HAZ for the normal group and for stunted group, HAZ 2SD will be selected
Exclusion criteria
Exclusion criteria: Allergies, intolerances, hypersensitivity, severe anemia (Hb <8dL), medication use, history of infectious diseases, physical or psychiatric, or surgical intervention.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| To evaluate the urinary metabolites as biomarkers for amino acid sufficiency in a short-term amino acid (lysine) supplementation in undernourished compared to healthy Indian Children.Timepoint: Baseline and at each 4 weeks during the 3 months | — |
Secondary
| Measure | Time frame |
|---|---|
| To develop the urinary metabolomic profiles for insufficiency and sufficiency states in undernourished Indian children, and to validate blood and urine metabolome during growth faltering.Timepoint: Baseline and at each 4 weeks during the 3 months | — |
Countries
India
Contacts
Public ContactDr Sarita Devi
St Johnâ??s Research Institute
Outcome results
None listed