Health Condition 1: K740- Hepatic fibrosis
Conditions
Interventions
Intervention1: Shear wave elastography: Using the LOGIQ S8 R3.1.9 software and the C1-6-D probe non invasively to check for liver stiffness.
This will be checked in 99 patients over a period of 12 mo
Sponsors
Father Muller Research Centre
Eligibility
Inclusion criteria
Inclusion criteria: 1.Men and women aged between 30 to 65 years who are diagnosed to have chronic liver disease based on supporting history and laboratory parameters. 2.History of significant alcohol consumption as defined by more than 21 units and 14 units of alcohol per week for males and females respectively. 3.Time interval between SWE and OGD 4.No history of consumption of beta blockers 5.No known prior liver insult â?? Infections, recreational drugs, autoimmunity, etc. 6.No previous history of upper gastrointestinal haemorrhage in the past
Exclusion criteria
Exclusion criteria: 1.Non alcoholic causes of liver cirrhosis. (Viral, toxins, extra-hepatic porto-venous obstruction and childhood history of paediatric cirrhosis) 2.Patients with ultrasongraphy findings of fatty liver 3.Patients with significant alcohol consumption who have alcoholic liver diseases in the stage of steato-hepatitis. 4.Patient on treatment with hepatotoxic drugs for an unrelated condition 5.Prior diagnosis of portal hypertension, oesophageal varices, hepatocelluar carcinoma, hepatic encephalopathy, portal vein thrombosis and liver trauma 6.Concomitant comorbidities such as heart failure â?? NYHA III and IV, acute asthma attack, recent myocardial infarction.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Aims to identify a cut off value which can accurately diagnose the presence of varices.Timepoint: 1 year | — |
Secondary
| Measure | Time frame |
|---|---|
| not applicableTimepoint: not applicable | — |
Countries
India
Contacts
Public ContactDr Susan Dsouza
FATHER MULLER MEDICAL COLLEGE
Outcome results
None listed