Health Condition 1: L400- Psoriasis vulgaris
Conditions
Interventions
Sponsors
Eligibility
Inclusion criteria
Inclusion criteria: CASES: All consenting adult patients (age 18 years to 60 years) visiting Yenepoya medical college hospital who are diagnosed to have Chronic plaque psoriasis. CONTROLS: Age and gender matched healthy volunteers
Exclusion criteria
Exclusion criteria: FOR CASES AND CONTROLS: Patients with inflammatory and infectious diseases, diabetes, pre-existing cardiovascular disease, hypertension, malignancies, pregnancy and lactation Ongoing systemic therapy in the last 3 months or topical steroid therapy for last 2 weeks
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Levels of mRNA expression of interleukins and tight junction proteins expressed in the skin of chronic plaque psoriasisTimepoint: Baseline at the time of visit | — |
Secondary
| Measure | Time frame |
|---|---|
| Correlation of the psoriasis disease severity with the levels of interleukins and barrier dysfunction markers. This will widen the knowledge about new targeted therapiesTimepoint: Baseline at the time of visit | — |
Countries
India
Contacts
Yenepoya Medical College