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Comparison of two drugs in brachial plexus block for upper limb surgeries

Comparison of two doses of dexmedetomidine as adjuvent to 0.5% Ropivacaine in ultrasound guided brachial plexus block in upper limb surgeries-A Randomised Control Trail

Status
Active, not recruiting
Phases
Unknown
Study type
Interventional
Source
CTRI
Registry ID
CTRI/2022/11/047461
Enrollment
60
Registered
2022-11-21
Start date
Unknown
Completion date
Unknown
Last updated
2023-01-09

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Health Condition 1: O- Medical and Surgical

Interventions

Intervention1: Brachial plexus block with ropivacaine and dexmedetomidine: 0.5 % Ropivacaine with 30 micrograms dexmedetomidine in brachial plexus block Control Intervention1: Brachial plexus block wi

Sponsors

Rohilkhand Medical College and Hospital
Lead Sponsor

Eligibility

Inclusion criteria

Inclusion criteria: American society of Anesthesiologist (ASA) grade I or II Posted for surgery of upper limb under ultrasound guided brachial plexus block.

Exclusion criteria

Exclusion criteria: Refusal by patient Patients taking anticoagulants, β- blockers or opioids, psychotropic medication. Patients with history of significantâ??neurological, psychiatric, neuromuscular, cardiovascular, pulmonary, renal or hepatic disease. Patients having history of drug and alcohol abuse. Patients with contraindication to Ropivacaine and dexmedetomidine. Women with pregnancy or lactating women. Patients on chronic analgesic therapy, diabetes or having coagulation disorders. Patient with infection at site of injection.

Design outcomes

Primary

MeasureTime frame
Onset of sensory block and duration of sensory block Onset of motor block and duration of motor block Duration of postoperative analgesiaTimepoint: The patient will be evaluated for sensory and motor block for every 2 minutes for first 20 minutes every 3 minutes for next 30 minutes, every 10 minutes for 60 minutes and finally every 15 minutes until the sensory and motor block regresses

Secondary

MeasureTime frame
Hemodynamic responses to the drug during and after surgery. Any complication or side effects.Timepoint: At 2,4,6,8,10,12,14,16,18,20,30,40,50, 60, 90, 120,180,240,360,480,720 minutes after the block, the ECG II lead, heart rate, systolic, diastolic, and mean blood pressure, and oxygen saturation will be recorded.

Countries

India

Contacts

Public ContactDr Pradeep Kumar

ROHILKHAND MEDICAL COLLEGE AND HOSPITAL

dr_malti_agrawal@yahoo.com9897897050

Outcome results

None listed

Source: CTRI (via WHO ICTRP) · Data processed: Feb 4, 2026