Health Condition 1: C539- Malignant neoplasm of cervix uteri, unspecified Health Condition 2: O- Medical and Surgical
Conditions
Interventions
Intervention1: Intraoperative lung protective ventilation: Lung recruitment manoeuvres by applying step wise increase in PEEP 30min after intubaion,30min after abdominal retraction,60min before extuba
Sponsors
NIMS
Eligibility
Inclusion criteria
Inclusion criteria: 1.Patients with 18-65years of age 2.either gender 3. patients undergoing elective open abdominal surgeries in trendelenburg position 4.surgery duration of greater than 2hours 5.American Society of Anesthesiologists (ASA) physical status I,II,III .
Exclusion criteria
Exclusion criteria: 1.Refusal to participate in the study 2.Preexisting significant cardiac or pulmonary co morbidities (heart failure, intractable shock, Chronic obstructive pulmonary disease, Asthma, pulmonary infection, bronchiectasis, pulmonary metastases) 3.Preexisting abnormalities on chest X-ray or spirometry. 4.History of neuromuscular disease 5.Liver cirrhosis (Child B or C), or chronic renal failure with hemodialysis, and the 6.Need to continue prolonged mechanical ventilation after surgery.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| intra- and postoperative changes in P/F.Timepoint: intra- and postoperative changes in P/F, PaO2 before induction, 1hour after intubation and postoperative day 1 | — |
Secondary
| Measure | Time frame |
|---|---|
| differences between the two groups regarding PaO2, A-aO2; intraoperative Cdyn and Stat, and the incidence of atelectasis detected on chest x-ray on the first postoperative day.Timepoint: differences between the two groups regarding PaO2, A-aO2; intraoperative Cdyn and Stat after intubation,30min after intubation,60min before extubation and at extubation, and the incidence of atelectasis detected on chest x-ray on the first postoperative day. | — |
Countries
India
Contacts
Public ContactNeeradi Vishal Kumar
Nizamâ??s Institute of Medical Sciences
Outcome results
None listed