Health Condition 1: J958- Other intraoperative and postprocedural complications and disorders of respiratory system, not elsewhere classified
Conditions
Interventions
None listed
Sponsors
AIIMS NEW DELHI
Eligibility
Inclusion criteria
Inclusion criteria: 1. Patients (18-65 years) intubated for a duration of more than 48 hours and on controlled mechanical ventilator admitted in intensive care units, AIIMS New Delhi due to any medical/surgical reason.
Exclusion criteria
Exclusion criteria: 1. Patients with pre-existing neuromuscular diseases (myasthenia gravis, Guillain-Barre syndrome, amyotrophic lateral sclerosis), cervical cord injury, diaphragmatic palsy 2. Pregnancy 3. Morbidly obese patient 4. Patients with poor diaphragmatic USG windows (presence of surgical dressings/ burns etc.) 5. Patients with a current pneumothorax or pneumomediastinum 6. Acute/worsening respiratory failure at or before day 3, any new onset respiratory failure defined as RR >35/min, P/F ratio 7. Patients extubated before day3 8. Patients on long term steroid treatment
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Correlation of cumulative fluid balance (CBF) with Diaphragm Thickness Fraction (DTF) at day 3 post intubationTimepoint: Day 3 post intubation | — |
Secondary
| Measure | Time frame |
|---|---|
| CBF with diaphragmatic excursion during spontaneous breathing trialsTimepoint: during spontaneous breathing trial after day 3;CBF with diaphragmatic excursion post extubationTimepoint: post extubation day 1 and 2;CBF with diaphragmatic thickness fraction at day 5and 7Timepoint: at day 5 and 7 post intubation;CBF with difficult/prolonged weaningTimepoint: more than 7 days;CBF with duration of mechanical ventilatorTimepoint: 7 days | — |
Countries
India
Contacts
Public ContactMANICHANDRA SINAM
All India Institute of Medical Sciences, New Delhi
Outcome results
None listed