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Comparison of incidence of post operative nausea and vomiting between two ways of induction of general anaesthesia

Comparing the effects of modified Rapid Sequence Induction (RSI) and standard induction on the incidence of postoperative nausea and vomiting (PONV) in moderate to high risk patients undergoing elective gynaecologic laparoscopic surgery - a randomised clinical trial

Status
Active, not recruiting
Phases
Unknown
Study type
Interventional
Source
CTRI
Registry ID
CTRI/2022/11/047420
Enrollment
128
Registered
2022-11-18
Start date
Unknown
Completion date
Unknown
Last updated
2022-11-21

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Health Condition 1: D10-D36- Benign neoplasms, except benign neuroendocrine tumors Health Condition 2: N70-N77- Inflammatory diseases of female pelvic organs Health Condition 3: C51-C58- Malignant neoplasms of female genital organs Health Condition 4: O- Medical and Surgical Health Condition 5: N80-N98- Noninflammatory disorders of female genital tract

Interventions

Intervention1: Rapid sequence induction: In this group, Rapid Sequence Induction and Intubation will be used to induce general anaesthesia, and patients will be followed up for a duration of 24 hours

Sponsors

JIPMER
Lead Sponsor

Eligibility

Inclusion criteria

Inclusion criteria: ASA I or II class Apfel score of 2 or more (moderate to high risk patients) Posted for surgeries expected to be completed in 4 hours or less

Exclusion criteria

Exclusion criteria: Pregnancy Patients requiring Ryleâ??s tube Anticipated difficult airway Surgeries that can result in entry of blood into stomach Patients in who succinylcholine is contraindicated

Design outcomes

Primary

MeasureTime frame
To compare the effects of modified Rapid Sequence Induction (RSI) and standard induction on the incidence of PONV in moderate to high risk patients undergoing elective gynaecologic laparoscopic surgery under general anaesthesiaTimepoint: 0, 6, 12 and 24 hours—

Secondary

MeasureTime frame
To compare the effects of modified Rapid Sequence Induction (RSI) and standard induction on the severity of PONV in moderate to high risk patients undergoing elective gynaecologic laparoscopic surgery under general anaesthesiaTimepoint: 0, 6, 12 and 24 hours;To compare the rescue anti emetic requirements among those undergoing modified Rapid Sequence Induction (RSI) and standard induction in moderate to high risk patients undergoing elective gynaecologic laparoscopic surgery under general anaesthesiaTimepoint: 0, 6, 12 and 24 hours—

Countries

India

Contacts

Public ContactAFSHAN

JIPMER

pankajkundra@gmail.com9367602030

Outcome results

None listed

Source: CTRI (via WHO ICTRP) · Data processed: Feb 4, 2026