FindTrial
Sign In

To study the effect of single agent tablet Zinc(50mg), Xylocaine (10%) spray and tablet zinc (50mg) along with Xylocaine (10%) spray when given together in reducing the incidence of postoperative sore throat in patients undergoing General Anaesthesia.

Effect of zinc tablet (50mg) vs Xylocaine (10%) spray vs zinc (50mg) along with Xylocaine (10%) spray on reducing the incidence of postoperative sore throat in intubated patients under General Anaesthesia.

Status
Active, not recruiting
Phases
Unknown
Study type
Interventional
Source
CTRI
Registry ID
CTRI/2022/11/047405
Enrollment
90
Registered
2022-11-17
Start date
Unknown
Completion date
Unknown
Last updated
2022-11-21

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Health Condition 1: O- Medical and Surgical Health Condition 2: O- Medical and Surgical

Interventions

Intervention1: Tablet Zinc acetate(50 mg): Tablet Zinc acetate (50 mg) given orally 30 minutes prior to intubation dissolved in 10 ml of water Control Intervention1: Xylocaine (10%) spray: Xylocaine

Sponsors

Dr Sivani Nanda
Lead Sponsor

Eligibility

Inclusion criteria

Inclusion criteria: 1. Age- 18 years to 60 years 2. ASA I to III

Exclusion criteria

Exclusion criteria: 1.Refusal of patient to participate in study 2.ASA IV 3.Patients allergic to Zinc or Xylocaine 4.Patients with history of other form of allergies 5.Patients with history of Pharyngitis/Tonsillitis/Laryngitis/any pre-existing pharyngeal or laryngeal pathologies 6.Confirmed or suspected case of COVID 19 7.Smokers 8.Surgeries extending more than 3 hours 9.Surgeries done in prone position as Glyccopyrolate will be required 10.Patients with difficult airway 11.Surgeries requiring nasal intubation

Design outcomes

Primary

MeasureTime frame
Incidence of post operative sore throat at 4 hours of extubationTimepoint: 4 hours after extubation—

Secondary

MeasureTime frame
DysphagiaTimepoint: 4 hours after extubation;DysphoniaTimepoint: 4 hours after extubation;HoarsenessTimepoint: 4 hours after extubation;Nausea, VomitingTimepoint: 4 hours after extubation—

Countries

India

Contacts

Public ContactDr Sivani Nanda

Institute of Medical Sciences and SUM Hospital

diptimayeemallik@soa.ac.in9861159151

Outcome results

None listed

Source: CTRI (via WHO ICTRP) · Data processed: Feb 4, 2026