Health Condition 1: C148- Malignant neoplasm of overlappingsites of lip, oral cavity and pharynx
Conditions
Interventions
Sponsors
Eligibility
Inclusion criteria
Inclusion criteria: 1.Adult patients with histopathological proven head and neck squamous cell carcinoma. 2.Locally advanced stage IV HNCs suitable for palliative radiotherapy treatment only.
Exclusion criteria
Exclusion criteria: 1.Patient treated previously with chemotherapy or radiotherapy. 2.Patients having diagnosis of carcinoma nasopharynx. 3.Patients having co-morbidities like uncontrolled diabetes, hypertension, thyroid disorders.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| 1. Quality of life assessment 2. Evaluation acute radiation toxicities 3. Response assessmentTimepoint: Patients will be assessed for quality of life before starting treatment and then at 6 monthly follow up. Patients will also be assessed weekly for radiation toxicities during treatment. Response to treatment will be assessed at 6 months. | — |
Secondary
| Measure | Time frame |
|---|---|
| Radiotherapy interruptions during treatmentTimepoint: Both treatment groups will be assessed for treatment interruptions- Group 1- After 1 week of start of treatment. Group 2-After 1 week and 2 weeks from start of treatment. | — |
Countries
India
Contacts
Post graduate institute of medical education and reseach, Chandigarh