Health Condition 1: A499- Bacterial infection, unspecified
Conditions
Interventions
None listed
Sponsors
Eligibility
Inclusion criteria
Inclusion criteria: Component 1 (passive surveillance) Passive surveillance will occur for cultures sent from designated wards. All GN isolates found to be CRO by local standard of care AST may be included. Component 2 (active surveillance) Patients will be considered for inclusion in active surveillance who are identified as part of a contact investigation for an index case of a critical CRO or possible nosocomial transmission event or are admitted to a ward designated for universal active surveillance. Component 3 (case investigation):Patients who have an isolate that is a critical CRO (rare or novel resistance mechanism or resistance to treatment) or identified as being part of possible nosocomial transmission will be included. Inpatient contacts identified through case investigation will be included. Component 4 (enhanced IPC) Individual patients will not be included in enhanced IPC. Wards selected for enhanced IPC will include ICUs and wards where critical CRO detection or nosocomial transmission is occurring.
Exclusion criteria
Exclusion criteria: Exclusion Criteria • Species not considered to be of concern for IPC activities • Age • Patient declines to participate in study activities
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| CRO, CP-CRO, and CR-CRO per 1,000 patient days. prevalence of CRO, CP-CRO, and CR-CRO colonization at admission. Changes in thefrequency of CRO, CP-CRO, and CR-CROTimepoint: six monthly | — |
Secondary
| Measure | Time frame |
|---|---|
| Change in technical capacity in bacteriology laboratories to detect and characterize CRO, CP-CRO, and CR-CROTimepoint: Baseline and endline | — |
Countries
India
Contacts
P. D. Hinduja Hospital and Medical Research Centre