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Clinical Study for the diagnosis of Eye infection

Ocular Pathogen Transcriptome Investigation using Comprehensive Sequencing (OPTICS)

Status
Active, not recruiting
Phases
Unknown
Study type
Observational
Source
CTRI
Registry ID
CTRI/2022/11/047357
Enrollment
100
Registered
2022-11-16
Start date
Unknown
Completion date
Unknown
Last updated
2024-05-27

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Health Condition 1: H36- Retinal disorders in diseases classified elsewhere

Interventions

None listed

Sponsors

Proctor Foundation
Lead Sponsor

Eligibility

Inclusion criteria

Inclusion criteria: 1. Presumed infectious anterior uveitis or intermediate uveitis or posterior uveitis or panuveitis 2. Presumed postoperative endophthalmitis 3. Unilateral or bilateral

Exclusion criteria

Exclusion criteria: 1. Insufficient specimen for metagenomic deep sequencing ( 2. Unable to give consent

Design outcomes

Primary

MeasureTime frame
To determine if metagenomic deep sequencing changes treatment or clinical therapy Timepoint: 9 weeks—

Secondary

MeasureTime frame
Proportion of patients with clinical improvement at final visitTimepoint: 8 weeks—

Countries

India, United States of America

Contacts

Public ContactDr S R Rathinam

Aravind Eye Hospital and Postgraduate Institute of Ophthalmology

rathinam@aravind.org914524356100

Outcome results

None listed

Source: CTRI (via WHO ICTRP) · Data processed: Feb 4, 2026