Health Condition 1: O94- Sequelae of complication of pregnancy, childbirth, and the puerperium
Conditions
Interventions
Intervention1: Melatonin Group: 5mg melatonin orally given 2 hours before spinal anaesthesia
Control Intervention1: Control Group: No drug given orally 2 hours before spinal anaesthesia
Sponsors
Postgraduate institute of medical education and research
Eligibility
Inclusion criteria
Inclusion criteria: Women in the reproductive age group of 18 to 45 years, ASA physical status I or II planned for elective caesarean section under spinal anesthesia would be recruited
Exclusion criteria
Exclusion criteria: 1.significant coexisting disease such as hepatorenal diseases 2. psychotic disorders 3. chronic cardiovascular disease 4. history of chronic headache 5. any contraindication to regional anesthesia such as local infection or bleeding disorders, allergy to melatonin, 6. long-term antidepressant or analgesic drug use
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Quality of recovery using QoR 10 scoreTimepoint: 24 hours after surgery | — |
Secondary
| Measure | Time frame |
|---|---|
| Adverse eventsTimepoint: immediately after surgery, 24 hours after surgery | — |
Countries
India
Contacts
Public ContactDivya Jain
Postgraduate institute of medical education and research
Outcome results
None listed