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Correlation of Ama status with specific Biomarkers in Patients of Sandhigata Vata (Osteo Arthritis)

Study on the assessment of Ama Status and its correlation with Advanced Glycation End Products and Lipid Peroxidation in patients of Sandhigata vata

Status
Active, not recruiting
Phases
Unknown
Study type
Observational
Source
CTRI
Registry ID
CTRI/2022/11/047327
Enrollment
162
Registered
2022-11-15
Start date
Unknown
Completion date
Unknown
Last updated
2022-11-21

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Health Condition 1: M150- Primary generalized (osteo)arthritis Health Condition 2: M150- Primary generalized (osteo)arthritis Health Condition 3: M150- Primary generalized (osteo)arthritis

Interventions

None listed

Sponsors

All India Institute of Ayurveda
Lead Sponsor

Eligibility

Inclusion criteria

Inclusion criteria: 1) Adult subjects of either sex between the age group of 30 to 70 years irrespective of chronicity. 2) Presence of cardinal sign and symptoms of Sandhigata vata. 3) Digital x-ray depicting the features of osteoarthritis. 4) Patients willing to incorporate themselves in the study.

Exclusion criteria

Exclusion criteria: 1) Severe cases of osteoarthritis with stiffness and immobility. 2) Any other conditions of the joints and bones like Rheumatoid arthritis and Ankylosing Spondylitis, Tubercular arthritis or infective Arthritis will be excluded. 3) Any malignant condition of the body. 4) Systemic diseases like Diabetes mellitus, Hypothyroidism etc. 5) Pregnancy

Design outcomes

Primary

MeasureTime frame
To assess status of ama in Sandhigata vata (Osteo Arthritis) along with assessment of Advanced glycation End product and Lipid peroxidation comparison with healthy individuals as control Study the relationship between the status of Ama, AGE and Lipid Peroxidation in patients of Sandhigata vata (Osteo Arthritis)Timepoint: At the time of first visit (Baseline)

Secondary

MeasureTime frame
To explore the corelation of Advanced Glycation End product with lipid peroxidation as a marker of oxidative stress in patients of Sandhigata vata. To study the relationship between disease activity score (with WOMAC Score) and Ama in the patients of Sandhigata vata.Timepoint: At the time of first visit (Baseline)

Countries

India

Contacts

Public ContactDr Pratik Sharma

All India Institute Of Ayurveda

vd.raishalini@gmail.com9389423843

Outcome results

None listed

Source: CTRI (via WHO ICTRP) · Data processed: Feb 4, 2026