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To compare which of the two nerve blocks is better in decreasing pain after total knee replacement surgery- adductor canal nerve block alone or adductor canal nerve block and genicular nerve block combined.

Analgesic efficacy of ultrasound-guided genicular nerve block in combination with adductor canal block: a randomized, double-blind, placebo-controlled trial

Status
Active, not recruiting
Phases
Unknown
Study type
Interventional
Source
CTRI
Registry ID
CTRI/2022/11/047318
Enrollment
50
Registered
2022-11-15
Start date
Unknown
Completion date
Unknown
Last updated
2022-11-21

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Health Condition 1: M171- Unilateral primary osteoarthritisof knee

Interventions

Intervention1: Bupivacaine, 0.25% Ropivacaine, Dexamethasone, Paracetamol, Celecoxib, Morphine: Group I: BLOCK GROUP - Adductor canal block+ genicular block â?? Ultrasound- guided adductor canal blo

Sponsors

Dr Prateek Mitra
Lead Sponsor

Eligibility

Inclusion criteria

Inclusion criteria: 1.American Society of Anaesthesiologists physical status (ASA) I-III 2.Aged 40 years and above. 3. Patients scheduled for unilateral, primary, total knee replacement under spinal anaesthesia 4.Patients who agree to participate in the study

Exclusion criteria

Exclusion criteria: 1.Patient refusal to participate 2.Contraindication to spinal anaesthesia or peripheral nerve blocks (local infection, neurologic deficit or disorder) 3.Patients with significant level of cognitive impairment (inability to communicate pain scores or the need of analgesia) 4.Patients on opioids for chronic pain 5.Revision knee surgery or bilateral TKR 6.History of psychiatric illness 7.Previous trauma or surgery of ipsilateral knee 8.Severe cardiovascular disease and renal disease 9.History of gastrointestinal bleeding or acid peptic disorder

Design outcomes

Primary

MeasureTime frame
The cumulative opioid consumption in the first 24 hoursTimepoint: First 24 hours following surgery—

Secondary

MeasureTime frame
-Visual analogue score (VAS) at rest and on passive 15° limb lifting at 3, 6,12 and 24 hours postoperatively. -Time to first rescue analgesic request -Patient´s satisfaction as per Likerts scale -Complications like nausea, vomiting, sedation, prolonged motor blockade Timepoint: 3,6,12 and 24 hours post operatively—

Countries

India

Contacts

Public ContactDr Ganesh Chandra Satapathy

Kalinga Institute of Medical Sciences

Ganesh.satapathy@kims.ac.in8283872939

Outcome results

None listed

Source: CTRI (via WHO ICTRP) · Data processed: Feb 4, 2026