Health Condition 1: I712- Thoracic aortic aneurysm, withoutrupture
Conditions
Interventions
None listed
Sponsors
Medanta The Medicity
Eligibility
Inclusion criteria
Inclusion criteria: All patients above 18 years of age giving consent eligible for Elective aortic surgery under Cardiopulmonary Bypass.
Exclusion criteria
Exclusion criteria: Patients below 18 years of age Patient did not provide consent Emergency surgery patients Patients undergoing aortic dissection Infective Endocarditis Moribund patients expected to die Patients receiving chemotherapy, immunosuppressants and steroids
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| 1. Intra and post operative hemodynamic stability as evidenced by relative difference of the vasopressor requirement. 2.Assessment of device related adverse events during study period.Timepoint: T1(Baseline) T2(2hours after Discontinuation of CPB) T3(24 hours after Discontinuation of CPB) T4(48 hours after Discontinuation of CPB) T5(15 days after Surgery) | — |
Secondary
| Measure | Time frame |
|---|---|
| Evaluation of IL-6,CRP,Procalcitonin,lactate levels. 2. Need and duration of renal replacement therapy. 3.Stroke/cerebrovascular accidents 4.low cardiac output: cardiac index2.0L/min/m2. 5.Duration of Mechanical Ventilation 6.30 day Mortality 7.Need for mechanical circulatory support (IABP/ECMO) 8.Multi organ dysfunction syndrome Timepoint: T1(Baseline) T2(2hours after Discontinuation of CPB) T3(24 hours after Discontinuation of CPB) T4(48 hours after Discontinuation of CPB) T5(15 days after Surgery) | — |
Countries
India
Contacts
Public ContactDr Mandeep Singh
Medanta The Medicity
Outcome results
None listed