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To compare between honey dressing, insulin dressing and normal saline dressing as to which dressing heals the wound faster.

A prospective randomized controlled open labelled study to evaluate the efficacy and safety of topical Insulin, Honey and Saline as wound dressings

Status
Active, not recruiting
Phases
Unknown
Study type
Interventional
Source
CTRI
Registry ID
CTRI/2022/11/047284
Enrollment
150
Registered
2022-11-14
Start date
Unknown
Completion date
Unknown
Last updated
2022-11-21

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Health Condition 1: L088- Other specified local infections of the skin and subcutaneous tissue

Interventions

Intervention1: Honey dressing: Honey will be applied over the wound daily. For 21 days. Intervention2: Topical insulin: Topical insulin will be applied over the wound daily. For 21 days. Control Inter

Sponsors

All India Institute of Medical Sciences, Nagpur
Lead Sponsor

Eligibility

Inclusion criteria

Inclusion criteria: • Infected Wounds â?? Presence of at least two of the following items in a wound: local swelling or induration, erythema, local tenderness or pain, local warmth, purulent discharge. • Traumatic Ulcers â?? Damage to skin, partial or full thickness, over any part of body due to trauma. • Diabetic Ulcers - A full-thickness wound, through the dermis, below the ankle on a weight-bearing or exposed surface in an individual with diabetes. • A pressure injury is localized damage to the skin and underlying soft tissue usually over a bony prominence or related to a medical or other device which can present as intact skin or an open ulcer and may be painful due to intense and/or prolonged pressure or pressure in combination with shear. • Venous Ulcers - Full-thickness defect of the skin, most frequently in the ankle region, that fails to heal spontaneously and is sustained by chronic venous disease.

Exclusion criteria

Exclusion criteria: • Perianal Wounds â?? Any wound whose margins are within 5 cm of the anal verge. • Patients with a known allergy to honey â?? As per history.

Design outcomes

Primary

MeasureTime frame
Reduction in wound area, % reduction of wound.Timepoint: After 3 weeks of dressings.—

Secondary

MeasureTime frame
Appearance of granulation tissue.Timepoint: Days;Eradication of infection (Culture swab reports)Timepoint: After every 3 days.;Length of hospital stay (days) till the wound healsTimepoint: Days;Pain relief (using the Visual Analogue Scale.)Timepoint: On day 5, 10, 15, 20 after commencement of topical application of respective agents.—

Countries

India

Contacts

Public ContactDr Siddharth P Dubhashi

All India Institute of Medical Sciences, Nagpur

spdubhashi@aiimsnagpur.edu.in

Outcome results

None listed

Source: CTRI (via WHO ICTRP) · Data processed: Feb 4, 2026