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Effect of Korean ginseng on semen analysis of male infertility

A prospective open label study of Ginseng (Korean Red Ginseng) as a food supplement in patients of male infertility.

Status
Active, not recruiting
Phases
Unknown
Study type
Interventional
Source
CTRI
Registry ID
CTRI/2022/11/047282
Enrollment
100
Registered
2022-11-14
Start date
Unknown
Completion date
Unknown
Last updated
2025-05-26

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Health Condition 1: E298- Other testicular dysfunction

Interventions

Intervention1: Korean Ginseng single arm prospective study: Effect of Korean Ginseng for 12 weeks on sperm quality and quantity Intervention2: Korean Red Ginseng: Impact of Korean red Ginseng for 12 w

Sponsors

Saveer Biotech Limited Immunity Bloom (Health Division)
Lead Sponsor
Fermish Clinical Technologies Pvt Limited
Collaborator

Eligibility

Inclusion criteria

Inclusion criteria: 1. Male participants, 25 - 45 years of age 2. Oligozoospermia (as confirmed by two different samples as per WHO 4th ed criteria) 3. Male Infertility (Unable to conceive even after 12 months of unprotected intercourse) 4. Participants who are willing to give consent

Exclusion criteria

Exclusion criteria: 1. Hypogonadotropic hypogonadism 2. History of traumatic injury to testes 3. A history of vasectomy or surgery for obstructive azoospermia 4. Hypergonadotropic hypogonadism with low serum testosterone (raised FSH >20) 5. Klinefelter Syndrome /Chromosomal abnormalities 6. Chronic alcoholism (current) 7. History of Chemotherapy or Radiotherapy to testes 8. Undetectable Inhibin B 9. Azoospermia 10. Chronic liver disease (liver enzymes elevated 2-fold higher than the normal range) 11. Renal Dysfunction (serum creatinine >1.5 mg/dl) 12. Anatomical abnormality of the genitals 13. History of surgical treatment received for male infertility 14. Medical treatment for infertility within last 4 weeks 15. Spontaneous retrograde flow in the internal spermatic vein +/- testicular atrophy, or testicular atrophy on Ultrasound 16. Patient on aspirin/warfarin

Design outcomes

Primary

MeasureTime frame
1.The qualitative and quantitative change in the semen quality after 12 weeks of from KRG consumption in the following parameters A.Sperm concertation B.Percentage Sperm motility C.Sperm morphology D.Sperm viability Timepoint: Baseline and 12 weeks—

Secondary

MeasureTime frame
1. Change in hormone parameter at 12 weeks A. Serum Testosterone B. Inhibin B C. Serum FSH D. Serum LH 2. The qualitative and quantitative change in the semen quality after 6 weeks of KRG consumption in the following parameters A. Sperm concertation B. Sperm motility C. Sperm morphology D. Sperm viability Timepoint: At Baseline 6 weeks and 12 weeks—

Countries

India

Contacts

Public ContactDr Ashwani Tandon

AIIMS Bhopal

rekha.endo@gmail.com07552835061

Outcome results

None listed

Source: CTRI (via WHO ICTRP) · Data processed: Feb 4, 2026