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EFFECTS OF PLATELET CONCENTRATE IN EXTRACTION SPACE CLOSURE IN ORTHODONTIC TOOTH MOVEMENT.

EVALUATION OF THE EFFECTS OF INJECTABLE - PLATELET RICH FIBRIN ON THE RATE OF EN MASSE EXTRACTION SPACE CLOSURE -A SINGLE CENTER RANDOMIZED CONTROLLED TRIAL

Status
Active, not recruiting
Phases
Phase 3
Study type
Interventional
Source
CTRI
Registry ID
CTRI/2022/11/047266
Enrollment
26
Registered
2022-11-14
Start date
Unknown
Completion date
Unknown
Last updated
2022-11-21

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Health Condition 1: K089- Disorder of teeth and supporting structures, unspecified

Interventions

Intervention1: INJECTABLE PLATELET RICH FIBRIN(i- PRF): 4ml of i-PRF is obtained from the patient blood sample by centrifugation.The study group will receive i-PRF two times: (1) prior to start of spa

Sponsors

parameshwari s
Lead Sponsor

Eligibility

Inclusion criteria

Inclusion criteria: 1.Patients with Angleâ??s Class I/ Class II div 1 malocclusion with anterior crowding (greater than 5mm) or bimaxillary protrusion requiring extraction of premolars. 2.Patients who are willing to undergo accelerated orthodontic procedures (after providing information sheet and obtaining informed consent)

Exclusion criteria

Exclusion criteria: 1.Patients with systemic illness, debilitating diseases 2.Patients with very poor oral hygiene with active periodontal diseases ,smoking habit 3.Patients with previous history of orthodontic treatment 4.Patients with gross skeletal and dentofacial deformities which require orthognathic surgery

Design outcomes

Primary

MeasureTime frame
RATE OF EN MASSE EXTRACTION SPACE CLOSURE. Rate of space closure will be checked at four weeks once until 3 months [FROM PATIENT STUDY MODELS]. Rate of space closure will be calculated by taking the average values of the extraction space from T0 to T3 Timepoint: outcome will be assessed at basline (To) , 4 weeks(T1), 8 weeks(T2) and 12 weeks(T3).

Secondary

MeasureTime frame
1.Change in the inclination in the anterior teeth. 2.pain evaluation.Timepoint: outcome will be assessed at basline (To) , 4 weeks(T1), 8 weeks(T2) and 12 weeks(T3).

Countries

India

Contacts

Public ContactParameshwari S

Indira Gandhi Institute of Dental Sciences

pavithranandammayappan@igids.ac.in9443183590

Outcome results

None listed

Source: CTRI (via WHO ICTRP) · Data processed: Feb 4, 2026