Health Condition 1: G89-G99- Other disorders of the nervous system Health Condition 2: G89-G99- Other disorders of the nervous system
Conditions
Interventions
Intervention1: Taurine: 3 grams of taurine supplementation orally per day in three divided doses (1000 mg) for six months.
Intervention2: Taurine: 3 grams of taurine supplementation orally per day in
Sponsors
King georges medical university,Department of Orhopaedic Surgery
Department of biochemistry
Eligibility
Inclusion criteria
Inclusion criteria: Inclusion criteria for controls Age and sex matched healthy controls were amongst the attendants of the ASCI subjects, having no known pathology and gave their consent to participate in the study. Inclusion criterion for ASCI subjects 1. Age 18 - 65 years of either gender, 2. ASCI 3. Complete motor injury (AIS-A, B)
Exclusion criteria
Exclusion criteria: Exclusion criterion for ASCI subjects 1. Other associated injuries such as major thoracoabdominal injuries & head injuries needing intervention. 2. Neuro-psychiatric patients and patients on steroid or other immunosuppressant therapy or other comorbid conditions making subjects unfit for surgery. 3. Subjects with non-vegetarian diet. 4. Subjects who do not give consent for participating in the study.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Taurine supplementation improves; AIS Scale, Sensory- Motor and SCIM and SF-36scores following in ASCI subjects.Taurine supplementation promotes Neurological Recovery.Timepoint: During Admission,3rd Week,3rd month,6th Month. | — |
Secondary
| Measure | Time frame |
|---|---|
| Taurine supplementation improves; AIS Scale, Sensory- Motor and SCIM and SF-36 scores following in ASCI subjects, other none targeted metabolites which are exceeding that variable importance on projection (VIP) scores greater than taurine then they will also be considered in this study.Timepoint: 8 month,12 month,24 month. | — |
Countries
India
Contacts
Public ContactZeenat Ara
KGMU
Outcome results
None listed