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To understand the role of magnesium and zinc in reducing the chances of sore throat following surgery

To compare the efficacy of magnesium and zinc tablets in decreasing the incidence of post operative sore throat

Status
Active, not recruiting
Phases
Unknown
Study type
Interventional
Source
CTRI
Registry ID
CTRI/2022/11/047238
Enrollment
150
Registered
2022-11-11
Start date
Unknown
Completion date
Unknown
Last updated
2022-11-21

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Health Condition 1: O- Medical and Surgical

Interventions

Intervention1: zinc and magnesium: Incidence and severity of post operative sore throat will be assessed at the 0th, 4th and 24th hour from the time of extubation in patients receiving zinc and magnes

Sponsors

Fluid Research Fund
Lead Sponsor

Eligibility

Inclusion criteria

Inclusion criteria: 1. Patients in the age group between 18 to 60 years 2. Patients belonging to American Society of Anaesthesiologists Physical status classification 1 and 2 3. Patients undergoing elective surgeries lasting for 1 to 6 hours

Exclusion criteria

Exclusion criteria: 1. Mallampatti grade of more than 2 2. More than two attempts at intubation 3. History of preoperative sore throat, upper respiratory tract infection, common cold or smoking 4. Patients receiving chronic treatment of non steroidal antiinflammatory agents, steroids, magnesium or zinc

Design outcomes

Primary

MeasureTime frame
To compare the incidence of post operative sore throat at the 4th hour from the time of extubation among patients receiving zinc, magnesium or placeboTimepoint: 4th hour after the end of surgery

Secondary

MeasureTime frame
To compare the incidence of post operative sore throat at the 0th, 4th, 12th and 24th hour from the time of extubation among patients receiving zinc, magnesium or placeboTimepoint: 0th, 4th, 12th and 24th hours from the time of extubation

Countries

India

Contacts

Public ContactLalrinhlui Renthlei

Christian Medical College, Vellore

ruthnmannam@gmail.com

Outcome results

None listed

Source: CTRI (via WHO ICTRP) · Data processed: Feb 4, 2026