Health Condition 1: O- Medical and Surgical
Conditions
Interventions
Intervention1: i.v. Esmolol versus i.v. Labetalol: Attenuation of hemodynamic responses (heart rate, systolic blood pressure, diastolic blood pressure, mean arterial pressure) associated with laryngo
Sponsors
Department of anaesthesiology SMS Medical college Jaipur
Eligibility
Inclusion criteria
Inclusion criteria: Patients willing to give written informed consent, ASA grade I & II Age groups 20-50 years Planned for elective surgery under general anesthesia.
Exclusion criteria
Exclusion criteria: H/O allergy to labetalol and esmolol , Anticipated difficult intubation, ASA grade III or greater, History of consumption of antihypertensive drugs, sedatives, hypnotics and antidepressants preoperatively, Pre-existing cardiovascular disease, significant respiratory, renal and hepatic disorder, bleeding disorder. History of drugs or alcohol abuse, Heart rate
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Attenuation of hemodynamic responses (heart rate, systolic blood pressure, diastolic blood pressure, mean arterial pressure) associated with laryngoscopy and intubation in elective surgeries under general anesthesia by injection esmolol 0.5mg/kg versus injection labetalol 0.25mg/kg intravenous.Timepoint: Readings are noted at baseline , 1 minute , 3 minute ,5 minute ,10 minutes after laryngoscopy and intubation. | — |
Secondary
| Measure | Time frame |
|---|---|
| To determine the difference in percentage of cases who experience adverse effects if any, of IV Esmolol and IV Labetalol.Timepoint: Readings are noted at baseline , 1 minutes , 3 minutes ,5 minutes ,10 minutes after laryngoscopy and intubation. | — |
Countries
India
Contacts
Public ContactDr Krishna Kant Sharma
SMS Medical College Jaipur
Outcome results
None listed