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A registry enabled antimicrobial stewardship quality improvement project in ICUs in India.

An evaluation of antimicrobial use and prescribing practices in ICUs in IRIS.

Status
Recruiting
Phases
Unknown
Study type
Observational
Source
CTRI
Registry ID
CTRI/2022/11/047161
Enrollment
5
Registered
2022-11-09
Start date
Unknown
Completion date
Unknown
Last updated
2023-02-06

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Health Condition 1: Z163- Resistance to other antimicrobialdrugs

Interventions

Intervention1: Antimicorbial stewardship -quality improvement initiative: We propose to leverage the existing registry infrastructure to enable surveillance of AMR in ICUs collaborating with IRIS and

Sponsors

The George Institue for Global Health India
Lead Sponsor

Eligibility

Inclusion criteria

Inclusion criteria: Invitation to participate will be open to all intensive care units within the participating hospitals of the IRIS network. Participation from a minimum of 4 and a maximum of 8 ICUs is sought. These are a mix of public, private and mixed setting hospitals, representative of all sectors catering to critical care in India.

Exclusion criteria

Exclusion criteria: ICUs which have established registry data collection of core, and daily Q (including quality indicators) to a completeness of >95% compliance will be selected.

Design outcomes

Primary

MeasureTime frame
1. The amounts of antimicrobial consumption by each ICU will be presented as defined daily doses (DDD) [36] and days of therapy (DOT) [37] per 1000 patient days and over all prescribing rate. 2. To provide assessment of the antimicrobial spectrum across various encounter types, an antimicrobial spectrum index tool will be applied to antimicrobial use data 3. The WHO policy guidance on integrated antimicrobial stewardship activities will be used to assess the ICU preparedness for AMS. 3. Guideline congruent therapy 4. Culture and sensitivity patterns. 5. In-depth interviews and FGD to identify human and organizational factors influence antimicrobial prescribing practices and concordance with existing AMS guidelines in the ICUTimepoint: Based on Objectives for each Research Question (RQ) RQ 1- 11 months RQ 2- 11 months RQ 3- 12 months

Secondary

MeasureTime frame
Adaptation of the Registry E-CRF for AMS related detailsTimepoint: RQ 1- 11 months

Countries

India

Contacts

Public ContactVivekanand Jha

The george institute for global health

vjha@georgeinstitute.org.in

Outcome results

None listed

Source: CTRI (via WHO ICTRP) · Data processed: Feb 4, 2026