Health Condition 1: O- Medical and Surgical
Conditions
Interventions
Intervention1: Dexmedetomidine: intrathecal injection 3mcg dexmedetomidine
Intervention2: clonidine: intrathecal injection of 30 mcg clonidine
Control Intervention1: Dexmedetomidine
: intrathecal inj
Sponsors
Sri Ramachandra Institute of Higher education and research
Eligibility
Inclusion criteria
Inclusion criteria: 1. Adult patients of both sexes 2. 18-60 years of age 3. ASA 1 and 2 4. Posted for elective lower limb surgeries and lower abdominal surgeries
Exclusion criteria
Exclusion criteria: • Patients on alpha 2 adrenergic antagonist, calcium channel blockers, ACE inhibitors • Coronary artery disease and valvular heart disease • Dysrhythmia • Body weight more than 120 kg • Height less than 140 cm • Post spinal surgeries, spinal deformities • H/o allergy to study drugs • Pregnancy • Coagulopathy • Neurological disorder
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| 1. Time of onset of sensory block from time of administration of spinal anesthesia till highest dermatomal level blocked 2. Time of onset of motor block from time of administering spinal anesthesia till MBS III attained 3. Duration of sensory block taken from time for two segment regression 4. Duration of motor block will be taKen as time to reach BMS 0 Timepoint: 0, 5,10,15,20,25, 30, 45,60min every 15 min thereon till desired outcome attained .... min | — |
Secondary
| Measure | Time frame |
|---|---|
| 1)Hemodynamic changes intraoperatively 2)Level of sedation intraoperatively 3)Any side effects associated with the two drugs 4) Duration of analgesiaTimepoint: 0, 5,10,15,20,25, 30,45,60 min every 15 min thereon till surgery is completed | — |
Countries
India
Contacts
Public ContactP Lekha Priyadharshini
Sri Ramachandra Institute Of Higher Education and Research
Outcome results
None listed