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Comparison of two drugs ( inj dexmedetomidine and inj clonidine) in terms of recovery from anaesthesia

Dexmedetomidine Versus Clonidine for Improved Quality of Emergence From General Anesthesia: A Comparative Study

Status
Active, not recruiting
Phases
Unknown
Study type
Interventional
Source
CTRI
Registry ID
CTRI/2022/11/047121
Enrollment
105
Registered
2022-11-09
Start date
Unknown
Completion date
Unknown
Last updated
2023-05-01

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Health Condition 1: K77- Liver disorders in diseases classified elsewhere Health Condition 2: C189- Malignant neoplasm of colon, unspecified Health Condition 3: C20- Malignant neoplasm of rectum Health Condition 4: C179- Malignant neoplasm of small intestine, unspecified Health Condition 5: O- Medical and Surgical Health Condition 6: O- Medical and Surgical Health Condition 7: K631- Perforation of intestine (nontraumatic)

Interventions

Intervention1: Dexmedetomidine and Clonidine: Drugs to be given before the end of surgery as infusion over 10 minutes Control Intervention1: Injection Dexmedetomidine: Injection Dexmedetomidine 1 Micr

Sponsors

RNT Medical College
Lead Sponsor

Eligibility

Inclusion criteria

Inclusion criteria: Patient of either age between 18 to 70 yrs with ASA grade 1 to 3 Estimated surgery time 1 to 4 hour under elective laprotomies

Exclusion criteria

Exclusion criteria: Patient refusal Allergy to study drug Preexisting uncontrolled hypertension, history of cerebrovascular accident, obesity, pregnancy and those on antidepressant therapy or chronic use of opioids or NSAIDS

Design outcomes

Primary

MeasureTime frame
Haemodynamic stabilityTimepoint: Intraoperatively (1- 3 hours)

Secondary

MeasureTime frame
Recovery profile, Side effectsTimepoint: Postoperative upto 24hr

Countries

India

Contacts

Public ContactDr Suman Goyet

RNT medical college and MB hospital

sandeepsubro@gmail.com9829025373

Outcome results

None listed

Source: CTRI (via WHO ICTRP) · Data processed: Feb 4, 2026