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Effect of brief episodes of ischaemia-reperfusion applied in distant tissues ,on endothelial dysfunction ( a type coronary artery disease) in women with polycystic ovarian syndrome

Effect of Remote Ischemic Pre-conditioning (RIPC) on Endothelial Dysfunction in Women with Polycystic Ovary Syndrome(PCOS)

Status
Active, not recruiting
Phases
Unknown
Study type
Interventional
Source
CTRI
Registry ID
CTRI/2022/11/047112
Enrollment
50
Registered
2022-11-07
Start date
Unknown
Completion date
Unknown
Last updated
2022-11-21

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Health Condition 1: R799- Abnormal finding of blood chemistry, unspecified

Interventions

Intervention1: Post RIPC group: intervention group will receive RIPC protocol of 4 cycles of 5 minutes each with occlusion to 220mmHg followed by 5 min re- perfusion. one intervention of 4 cycles amou

Sponsors

Institute of medical sciences
Lead Sponsor

Eligibility

Inclusion criteria

Inclusion criteria: Case known of classical PCOS

Exclusion criteria

Exclusion criteria: Thyroid dysfunction Cushing syndrome Late onset of congenital adrenal hyperplasia Pregnancy and breastfeeding Use of glucocorticoids, OCPs, ovulatory agents within 3 months of study Smoking, drug and alcohol abuse

Design outcomes

Primary

MeasureTime frame
maximum percentage increase in flow after cuff deflation compared to baseline flowTimepoint: 4 cycles of 5 minutes each with occlusion to 220 mmHg followed by 5 min re- perfusion another intervention of 4 cycles of 35 minutes daily for 7 days—

Secondary

MeasureTime frame
nilTimepoint: nil—

Countries

India

Contacts

Public ContactDr Bhupendra Verma

Department of Obstetrics and Gynaecology

shikhasachan08@yahoo.com

Outcome results

None listed

Source: CTRI (via WHO ICTRP) · Data processed: Feb 4, 2026