Health Condition 1: L509- Urticaria, unspecified
Conditions
Interventions
None listed
Sponsors
sushil kumar singh
Eligibility
Inclusion criteria
Inclusion criteria: Patient of chronic urticaria presenting in the outpatient department of Dermatology.
Exclusion criteria
Exclusion criteria: Acute urticaria 2. Angioedema without urticaria 3. Patients of CSU who has taken steroids or immunosuppressive in the last four weeks 4. Urticarial syndromes like Schnitzler's syndrome etc. 5. Other causes of urticarial rashes like lesion associated with systemic lupus, mastocytosis 6. Urticarial vasculitis 7. Age below 12 years 8. Special groups such as pregnancy.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Demographic profile of patients 2. Clinical profile of the disease including disease duration 3. Disease severity at presentation measured with UAS7 scores 4. Autoreactivity determined by ASST positivity 5. Blood tests including anti-TPO antibodies, ANA (hep 2), IgE, and rheumatoid factor to find out possible association with autoimmune disease.Timepoint: 18 months | — |
Secondary
| Measure | Time frame |
|---|---|
| To find out the proportion of autoreactive cases amongst the patients of CU by ASST 2. To find out the presence of autoantibodies like rheumatoid factor, ANA (Hep2), and anti-TPO antibodies 3. To find out disease association of CU with other autoimmune or allergic diseases 4. To find out the presence of physical inducibility in patients of CU 5. To correlate disease severity (by UAS7 score) and disease duration with the presence of signs of autoimmunity (presence of autoantibodies and ASST positivity)Timepoint: 18 months | — |
Countries
India
Contacts
Public ContactSUSHIL KUMAR SINGH
calcutta national medical college
Outcome results
None listed