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Incidence and risk factors of higher antibiotic resistant bacteria in ICU patients

Incidence of polymyxin B, tigecycline and minocycline resistant Acinetobacter baumannii causing ventilator-associated pneumonia or hospital acquired pneumonia among intensive care unit patients and determination of risk factors for adverse outcomes.

Status
Active, not recruiting
Phases
Unknown
Study type
Observational
Source
CTRI
Registry ID
CTRI/2022/11/047072
Enrollment
200
Registered
2022-11-04
Start date
Unknown
Completion date
Unknown
Last updated
2022-11-21

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Health Condition 1: J156- Pneumonia due to other Gram-negative bacteria

Interventions

Intervention1: NIL: NIL

Sponsors

Souvik Chaudhuri
Lead Sponsor

Eligibility

Inclusion criteria

Inclusion criteria: 1. Patients aged 18-90 years and newly diagnosed VAP or HAP. 2.Clinical suspicion of VAP with the following criteria â?? More than 48 hours of endotracheal intubation and ventilation, chest x-ray showing new, persisting, progressive chest infiltrates, clinical symptoms of fever, leucopenia ( =12,000/µL), new onset purulent sputum, increased oxygen requirement, worsening gas exchange, temperature >38°C or 100.4°F. 3.HAP contracted in a patient with at least 48 hours of hospital stay.

Exclusion criteria

Exclusion criteria: Pediatric age group Patients who are not intubated and not on invasive mechanical ventilation. Patients with

Design outcomes

Primary

MeasureTime frame
Ventilator associated pneumonia (VAP) due to Acinetobacter baumanniiTimepoint: 72 hours, 1 week, 10 days, 14 days.

Secondary

MeasureTime frame
MortalityTimepoint: 28 days after ICU admission

Countries

India

Contacts

Public ContactSouvik Chaudhuri

Kasturba Medical College, Manipal, Manipal Academy of Higher Education

souvik.chaudhuri@manipal.edu9937178620

Outcome results

None listed

Source: CTRI (via WHO ICTRP) · Data processed: Feb 4, 2026