EFFICACY OF INJECTABLE PLATELET RICH FIBRIN ON ACCELERATING MOLAR DISTALISATION DURING EN MASSE RETRACTION USING INFRAZYGOMATIC CREST IMPLANTS -A RANDOMISED CONTROL TRIAL

EFFICACY OF INJECTABLE PLATELET RICH FIBRIN ON ACCELERATING MOLAR DISTALISATION DURING EN MASSE RETRACTION USING IZC -A RANDOMISED CONTROL TRIAL

Status

Active, not recruiting

Phases

Phase 3Phase 4

Study type

Interventional

Source

CTRI

Registry ID

CTRI/2022/11/047070

Enrollment

Registered

2022-11-04

Start date

Unknown

Completion date

Unknown

Last updated

2022-11-21

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Health Condition 1: M262- Anomalies of dental arch relationship Health Condition 2: M262- Anomalies of dental arch relationship Health Condition 3: K088- Other specified disorders of teethand supporting structures

Interventions

Intervention1: Injectable Platelet Rich Fibrin (i-PRF): Platelet Rich Fibrin is a second generation platelet containing concentrate and has been used extensively in wound healing. PRF traps platelets

Eligibility

Inclusion criteria

Inclusion criteria: 1. PATIENTS REQUIRING IZC AIDED EN MASSE RETRACTION WITH EXTRACTION OF 8â??s 2. AGED -18-35 YEARS 3. NO SYSTEMIC ILLNESS, ABSENCE OF BONE METABOLIC DISORDERS. 4. PERIODONTALLY HEALTHY SUBJECTS. 5. GOOD ORAL HYGIENE. 6. PATIENTS WITHIN THE ACCEPTABLE UNIFORM RANGE OF BONE DENSITY.

Exclusion criteria

Exclusion criteria: 1. PATIENTS WITH SYSTEMIC ILLNESS, BONE METABOLIC DISORDERS. 1.PERIODONTALLY COMPROMISED SUBJECTS.

Design outcomes

Primary

Measure	Time frame
rate of molar distalisationTimepoint: rate of molar distalisation at first, third and fifth month	—

Secondary

Measure	Time frame
level of alkaline phosphatase and acid phosphatase in gingival crevicular fluid.Timepoint: start of retraction, end of five months.	—

Countries

India

Contacts

Public ContactDeepika Katyal

Saveetha Dental College and Hospital, Tamilnadu

ashwin.george10@gmail.com

Outcome results

None listed

Source: CTRI (via WHO ICTRP) · Data processed: Feb 4, 2026