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Evaluation of combined effect of Triphala and Aloe vera in patients with Oral Submucous Fibrosis: A Randomized Controlled Trial.

Comparative evaluation of efficacy of Triphala and Aloe vera with lycopene in patients with Oral Submucous Fibrosis: A Randomized Controlled Trial.

Status
Active, not recruiting
Phases
Unknown
Study type
Interventional
Source
CTRI
Registry ID
CTRI/2022/11/047069
Enrollment
60
Registered
2022-11-04
Start date
Unknown
Completion date
Unknown
Last updated
2024-01-22

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Health Condition 1: K135- Oral submucous fibrosis

Interventions

Intervention1: Triphala and Aloe Vera: Patient will be prescribed with Triphala tablet 500 mg + 30 ml of Aloe vera Juice once daily and topical application of 2% Triphala gel + 5mg Aloe Vera gel, 2 ti

Sponsors

Dr Komal Deotale
Lead Sponsor

Eligibility

Inclusion criteria

Inclusion criteria: Patients with stage 2 OSMF with i.e mouth opening between 25mm-35mm according to Chandramani More Classification.

Exclusion criteria

Exclusion criteria: 1. Patients with other intra oral lesions. 2. Patients with known hypersensitivity to triphala and aloe vera. 3. Patients with prior treatment for OSMF.

Design outcomes

Primary

MeasureTime frame
Use of Triphala and Aloe vera in OSMF patients increases mouth opening, reduces burning sensation and increases tongue protrusion and are measured and recorded at baseline, 1st and 2nd month.Timepoint: Pre-operative Burning Sensation, Interincisal Mouth Opening and Tongue protrusion will be measured. These clinical parameters will be measured and recorded at baseline, 1st and 2nd month.

Secondary

MeasureTime frame
Triphala and Aloe Vera are as efficacious as lycopene in management of OSMF in terms of increase in mouth opening, reduction in burning sensation and increase in tongue protrusion. All these parameters will be measured and recorded at baseline,at every 15th day and after 2 months.Timepoint: Baseline,at every 15th day and after 2 months.

Countries

India

Contacts

Public ContactDr Ashish Lanjekar

Swargiya Dadasaheb Kalmegh Smruti Dental College And Hospital

ashish.lanjekar@sdk-dentalcollege.edu.in9595052481

Outcome results

None listed

Source: CTRI (via WHO ICTRP) · Data processed: Feb 4, 2026