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Comparative Study of two drugs to start labour pains in pregnancy

"Oral mifepristone versus misoprostol for pre-induction cervical ripening and term induction of labour- A randomized controlled trial"

Status
Active, not recruiting
Phases
Unknown
Study type
Interventional
Source
CTRI
Registry ID
CTRI/2022/11/047064
Enrollment
100
Registered
2022-11-04
Start date
Unknown
Completion date
Unknown
Last updated
2022-11-21

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Health Condition 1: O80- Encounter for full-term uncomplicated delivery

Interventions

Intervention1: oral mifepristone versus misoprostol for pre-induction cervical ripening and term induction of labour: Mifepristone- 100mcg- oral-single dose - 24 hrs Misoprostol- 25 mcg - vaginal- 2 d

Sponsors

Dr Ranjana Gupta
Lead Sponsor

Eligibility

Inclusion criteria

Inclusion criteria: 1.Uncomplicated pregnancy 2.Singleton live pregnancy with cephalic presentation 3.Term pregnancy (37 - 42 weeks) 4.Intra uterine foetal death 5.Gestational hypertension 6.Primigravida less than 35 years 7.uncomplicated multigravida up to three pregnancies 8.Intact membranes during the time of induction 9.No contraindications for prostaglandins or mifepristone.

Exclusion criteria

Exclusion criteria: 1.Premature membrane rupturing 2.Malpresentations 3.Cephalopelvic disproportion 4.Bad obstetric history or history of previous abortions 5.Previous history of caesarean section or any uterine surgery 6.Multiple pregnancy 7.Placental complications like abruption or placenta praevia 8.Abnormal pattern of foetal heartbeat 9.Parity > 4 10.Active herpes infection 11.Contra indication for prostaglandins

Design outcomes

Primary

MeasureTime frame
â?¢To evaluate the efficacy of oral mifepristone versus misoprostol for pre-induction cervical ripening and term induction of labour.Timepoint: 24 hrs

Secondary

MeasureTime frame
NillTimepoint: nill

Countries

India

Contacts

Public ContactDr Shweta kumari

Rohilkhand medical college and hospital

ranj2036@gmail.com7351326155

Outcome results

None listed

Source: CTRI (via WHO ICTRP) · Data processed: Feb 4, 2026