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Comparison of HACOR and ROX score to predict failure of Non-invasive respiratory assist devices like NIV, HFNC

comparison of ROX index and HACOR score for predicting failure of non invasive respiratory therapy in acute hypoxemic respiratory failure

Status
Recruiting
Phases
Unknown
Study type
Observational
Source
CTRI
Registry ID
CTRI/2022/11/047053
Enrollment
192
Registered
2022-11-04
Start date
Unknown
Completion date
Unknown
Last updated
2024-03-04

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Health Condition 1: J960- Acute respiratory failure

Interventions

None listed

Sponsors

Bharati Hospital and Research centre
Lead Sponsor

Eligibility

Inclusion criteria

Inclusion criteria: All Patients who are 18 years of age or older will be screened for AHRF, defined as tachypnea (respiratory rate > 25/ min), PaO2/FiO2 ratio Patients with AHRF who fail COT will be identified by any of the following criteria- 1. Worsening tachypnea (RR > 35) , 2. Oxygen saturation 3. Signs of respiratory distress( decreased consciousness, tachycardia, paradoxical respiratory movements, use of accessory muscles)

Exclusion criteria

Exclusion criteria: 1) Chronic respiratory failure, 2) Hemodynamic instability (systolic BP 0.1 mcg/kg/min or Dopamine requirement > 10mcg/kg/min ) 3) A do-not-intubate order 4) Anticipated life expectancy less than 90 days

Design outcomes

Primary

MeasureTime frame
Predicting failure of non invasive respiratory therapy (Both HFNC and NIV) in acute hypoxemic respiratory failure by calculating ROX index and HACOR scoreTimepoint: At 1 hour and 6 hours of initiation of NIV or HFNC—

Secondary

MeasureTime frame
To compare effectiveness of ROX index and HACOR score for predicting failure of non invasive respiratory therapy (NIV and HFNC) as defined by need of intubationTimepoint: 18 months;To study predictors of failure of non invasive respiratory therapyTimepoint: 18 months—

Countries

India

Contacts

Public ContactDr Manoj Raju Prabandhankam

Bharati Vidyapeeth (Deemed to be University) Medical College

drshahjignesh78@gmail.com9028246946

Outcome results

None listed

Source: CTRI (via WHO ICTRP) · Data processed: Feb 4, 2026