None listed
Conditions
Interventions
Intervention1: Tranexamic acid 1 grams: administered 10 minutes before skin incision in a dosage of 1 gram intravenous slowly infused over 5 minutes
Control Intervention1: placebo injection normal sal
Sponsors
Dr Krishna Memakiya
Eligibility
Inclusion criteria
Inclusion criteria: 1)Age > 18 year 2)Cesarean delivery, either before or during labor 3)Gestational age >= 34 weeks 4)Prenatal hemoglobin level in the week before the cesarean > 9 gm% 5)Signed informed consent
Exclusion criteria
Exclusion criteria: 1)History of venous (deep vein thrombosis and/or pulmonary embolism) or arterial (angina pectoris,myocardial infarction, or stroke) thrombosis 2) History of epilepsy or seizure 3) Any known active cardiovascular, renal or liver disorders 4) Autoimmune disease 5) Sickle cell disease 6) Severe hemorrhagic disease 7) Abnormally invasive placenta (placenta accrete /increta/percreta) 8) Abruptio placentae and placenta previa 9) Eclampsia or HELLP (Hemolysis Elevated Liver Low Platelet) syndrome 10) In utero fetal death 11) Administration of low-molecular-weight heparin or antiplatelet agents in the week before delivery 12) Known hypersensitivity to tranexamic acid or concentrated hydrochloric acid 13) Cesarean delivery for the second twin or second/ third triplet(s) after vaginal birth of the first twin
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| the amount of blood loss from the end of placental delivery to the end of . two hours post partumTimepoint: end of two hours post partum | — |
Secondary
| Measure | Time frame |
|---|---|
| the difference in haemoglobin % post operatively(24 hours after the cesarean section) among both groupTimepoint: the difference in haemoglobin % post operatively (24 hours after the cesarean section)among both group | — |
Countries
India
Contacts
Public ContactDr Ashish Vishnu Gokhale
baroda medical college
Outcome results
None listed