Health Condition 1: O- Medical and Surgical
Conditions
Interventions
Intervention1: Dexmedetomidine: Induction-1mcg/kg
Maintenance-0.5mgc/kg/hr till the end of surgical procedure (1 to 3 hours)
Control Intervention1: Fentanyl: Induction-1mcg/kg
maintenance-0.5mcg/kg/hr
Sponsors
Lady Hardinge Medical College
Eligibility
Inclusion criteria
Inclusion criteria: ASA I and II
Exclusion criteria
Exclusion criteria: 1. Laparoscopic surgery with an anaesthetic duration of >3hours. 2. Any known allergy to drugs used in the study. 3. BMI > 35. 4. Known psychiatric illness. 5. Addiction to drugs and alcohol. 6. Chronic opioid therapy.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Mean/ Median effect site concentration (EC50) of propofol with fentanyl or dexmeditomidine will be compared by using Student’s t test/ Mann Whitney U test.Timepoint: At the end of anaesthesia | — |
Secondary
| Measure | Time frame |
|---|---|
| 1 Number of patients having side effects 2 Mean time to achieve modified aldrete score more than equal to 9 3 Number of patients having post operative nausea vomitting 4 Mean analgesic requirement in post operative periodTimepoint: 1 After stopping total intravenous infusion 2 After stopping total intravenous infusion 3 First 24 hours post operative period 4 First 24 hours post operative period | — |
Countries
India
Contacts
Public ContactAnkita Singh
Lady Hardinge Medical College
Outcome results
None listed