Health Condition 1: A309- Leprosy, unspecified
Conditions
Interventions
Intervention1: Autologous Platelet rich Plasma: 1 ml of Freshly prepared autologous Platelet rich plasma given perineurally within 15 minutes of preparation, in patients of Hansens disease with ulnar
Sponsors
AIIMS Bhopal
Eligibility
Inclusion criteria
Inclusion criteria: 1. Known case of Hansen’s disease on or post treatment with Multi drug therapy 2. Age: =18 years 3. Patients of Hansen’s disease with peripheral neuropathy involving Ulnar and/ or Common Peroneal Nerve with residual impairment 4. Willingness to participate in study (informed written consent) 5. Willingness to forego any other concomitant treatment modality
Exclusion criteria
Exclusion criteria: 1. Hansen’s disease diagnosed for more than three years duration. 2. Signs of active inflammation or abscess around the Ulnar or Common Peroneal Nerve 3. Diagnosed case of active lepra reaction 4. Infection at the site of injection 5. Reduced range of motion of knee, elbow, wrist or ankle 6. Abnormal radiograph of elbow joint and knee joint of the affected side 7. Received local steroid injection within 6 months, NSAIDS within one week prior to intervention or on systemic steroids more than 20 mg daily 8. Abnormal haemoglobin or blood count (platelet count , Hb g/dl,Mean platelet volume >12.3 fl) 9. Use of anti-platelet medications 10. Uncontrolled Diabetes Mellitus (FBS >125 mg/dl or PPBS >200 mg/dl) 11. Known case of severe cardiac, liver or renal disease 12. Pregnancy or lactation 13. Unwillingness to participate in study
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| two point discrimination testTimepoint: 0,6, 12 weeks | — |
Secondary
| Measure | Time frame |
|---|---|
| total area of sensory impairment, Nerve conduction study, dynamometry and manual muscle power testing, SALSA scale scoreTimepoint: 0,6, 12 weeks | — |
Countries
India
Contacts
Public ContactAnyesha Saha
AIIMS Bhopal
Outcome results
None listed