Health Condition 1: C56- Malignant neoplasm of ovary
Conditions
Interventions
Intervention1: TIVA (total intravenous anaesthesia): propofol will be used for anaesthesia maintenance
Control Intervention1: Inhalational anesthesia: inhalation anaesthetic agent for anaesthesia mai
Sponsors
All India Institute of Medical Sciences Jodhpur
Eligibility
Inclusion criteria
Inclusion criteria: Female patients aged between 25-75yrs (American society of anaesthesiologist grading I â?? III) undergoing surgery for gynaecological cancer will be included.
Exclusion criteria
Exclusion criteria: 1.Patients not willing to participate in the study 2.ASA > III 3.Patient underwent previous surgery except diagnostic biopsy 4.Any contraindication to use of study drug 5.Any ongoing infection in patient 6.Any other chronic inflammatory condition as RA, inflammatory bowel disease etc. 7.Secondary sepsis and/or septic shock with an underlying condition 8.Active infection such as severe peritonitis, pancreatitis, or trauma 9.Long-term ICU stay 10.Pre Existing immunodeficiency.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| â??To compare difference in change of post-operative and preoperative NLR (Day 3-preoperative) in both the groups.Timepoint: day 3 | — |
Secondary
| Measure | Time frame |
|---|---|
| To compare changes in level of post-operative and preoperative platelet lymphocyte ratio (PLR), monocyte lymphocyte ratio (MLR), mean platelet volume to platelet count ratio(MPV/PC), (Day 3-Preoperative) in both groups.Timepoint: Day 3 | — |
Countries
India
Contacts
Public ContactPriyanka Sethi
All India Institute of Medical Sciences, Jodhpur
Outcome results
None listed